Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 10/20 | 0.56 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656020 | 0.91 | CAPN1 (0.62) | CASP1CTSKCTSLCAPN1CTSB | |
| SCHEMBL10453892 | 0.90 | CAPN1 (0.61) | CASP1CTSKCAPN1 | |
| SCHEMBL30819309 | 0.89 | CTSL (0.65) | CTSKCTSLCAPN1CTSSCTSB | |
| SCHEMBL11697811 | 0.88 | ECE1 (0.59) | CASP1CTSKCTSB | |
| SCHEMBL11693784 | 0.87 | CTSK (0.64) | CTSKPSMB1CTSLCAPN1CTSS | |
| SCHEMBL17841948 | 0.87 | CTSK (0.56) | CASP1CTSKCTSLCAPN1 | |
| SCHEMBL6159279 | 0.86 | CASP1 (0.64) | CASP1CTSL | |
| SCHEMBL8553630 | 0.86 | CASP1 (0.64) | CASP1CTSL | |
| SCHEMBL591895 | 0.86 | CTSK (0.59) | CTSKCTSLCTSSCTSB | |
| SCHEMBL2627373 | 0.86 | CTSK (0.59) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012367-A | Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto | G. D. SEARLE & CO. (US) | 1977-03-15 | — | — | US | disclosed |