Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795426 | 0.71 | ACHE (0.42) | ALDH1A1GAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL2155273 | 0.70 | AOC3 (0.51) | POLBAOC3L3MBTL1MAPK1ACHE | |
| SCHEMBL8756705 | 0.68 | AOC3 (0.49) | MEN1KMT2AAOC3ADRA2AADRA1A | |
| SCHEMBL6016443 | 0.68 | CA12 (0.46) | ALDH1A1ADRA2AADRA1ACYP2D6BCHE | |
| SCHEMBL28532165 | 0.68 | AOC3 (0.49) | ALDH1A1MEN1KMT2APOLBAOC3 | |
| SCHEMBL23922746 | 0.68 | TYR (0.64) | MEN1KMT2AAOC3L3MBTL1CYP2D6 | |
| SCHEMBL29492462 | 0.68 | TYR (0.64) | MEN1KMT2AAOC3L3MBTL1CYP2D6 | |
| SCHEMBL31404218 | 0.67 | AOC3 (0.44) | ALDH1A1POLBAOC3L3MBTL1ACHE | |
| SCHEMBL1758212 | 0.67 | AOC3 (0.47) | MEN1KMT2AAOC3L3MBTL1ACHE | |
| SCHEMBL7284507 | 0.67 | CYP2D6 (0.50) | ALDH1A1GAAMEN1KMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401517-A1 | Substituted 2-alkynylphenols with anti-inflammatory action, a process for their preparation and pharmaceutical compositions thereof | CAMILLO CORVI S.p.A. (IT) | 1990-12-12 | — | — | EP | disclosed |