Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455346 | 0.82 | CYP2C9 (0.56) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL10455347 | 0.82 | CYP2C9 (0.56) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL10454499 | 0.82 | CYP2C9 (0.56) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL10455515 | 0.82 | CYP2C9 (0.56) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL10455777 | 0.81 | CCR3 (0.44) | RORCALDH1A1ACSL1PDE4APDE4B | |
| SCHEMBL10455763 | 0.81 | RORC (0.41) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL10454493 | 0.81 | RORC (0.43) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL10454500 | 0.80 | RORC (0.41) | RORCALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL10455483 | 0.80 | RORC (0.41) | RORCACSL1PDE4APDE4BPDE4C | |
| SCHEMBL9765552 | 0.80 | RORC (0.41) | RORCACSL1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |