Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 3/20 | 0.41 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.41 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455809 | 0.82 | EPHX2 (0.43) | ACSL1ACSL3ACSL6ELANEDGAT1 | |
| SCHEMBL10454525 | 0.80 | KMT2A (0.53) | ACSL1ACSL3ACSL6ELANEDGAT1 | |
| SCHEMBL10455781 | 0.79 | ELANE (0.57) | ACSL1ACSL3ACSL6ELANEDGAT1 | |
| SCHEMBL10455484 | 0.78 | KMT2A (0.42) | ELANEDGAT1EPHX2FAAHCYP2C19 | |
| SCHEMBL10455517 | 0.78 | KMT2A (0.42) | ELANEDGAT1EPHX2FAAHCYP2C19 | |
| SCHEMBL10454520 | 0.76 | ACSL1 (0.43) | ACSL1ACSL3ACSL6ELANEKCNH2 | |
| SCHEMBL10455806 | 0.76 | ELANE (0.45) | ELANEEPHX2FAAH | |
| SCHEMBL10454502 | 0.75 | ACSL1 (0.43) | ACSL1ACSL3ACSL6KCNH2 | |
| SCHEMBL10454523 | 0.75 | MAPT (0.54) | EPHX2FAAH | |
| SCHEMBL26857799 | 0.74 | AKR1C3 (0.51) | ACSL1ACSL3ACSL6DGAT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |