Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455517 | 1.00 | KMT2A (0.42) | KMT2AP2RX7EPHX2TSHRCYP2C9 | |
| SCHEMBL10454525 | 0.90 | KMT2A (0.53) | KMT2AEPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455809 | 0.88 | EPHX2 (0.43) | EPHX2ELANEDGAT1FAAHALDH1A1 | |
| SCHEMBL10455778 | 0.84 | RORC (0.38) | KMT2AEPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455487 | 0.84 | EPHX2 (0.39) | EPHX2ELANEDGAT1FAAHRORC | |
| SCHEMBL10454523 | 0.82 | MAPT (0.54) | KMT2AEPHX2TSHRCYP2C9FAAH | |
| SCHEMBL10455757 | 0.82 | ACSL1 (0.40) | KMT2AEPHX2ELANEDGAT1FAAH | |
| SCHEMBL10455781 | 0.82 | ELANE (0.57) | EPHX2ELANEDGAT1FAAHALDH1A1 | |
| SCHEMBL10455761 | 0.82 | P2RX7 (0.43) | P2RX7EPHX2TSHRRORCNOTUM | |
| SCHEMBL10455774 | 0.82 | P2RX7 (0.43) | P2RX7EPHX2TSHRRORCNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0210772-A2 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |