Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.38 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455484 | 0.88 | KMT2A (0.42) | EPHX2ELANEDGAT1FAAHRORC | |
| SCHEMBL10455517 | 0.88 | KMT2A (0.42) | EPHX2ELANEDGAT1FAAHRORC | |
| SCHEMBL10454525 | 0.87 | KMT2A (0.53) | EPHX2ELANEDGAT1FAAHACSL1 | |
| SCHEMBL10455781 | 0.86 | ELANE (0.57) | EPHX2ELANEDGAT1FAAHACSL1 | |
| SCHEMBL10455806 | 0.85 | ELANE (0.45) | EPHX2ELANEFAAHALDH1A1POLB | |
| SCHEMBL10455500 | 0.82 | ACSL1 (0.41) | EPHX2ELANEDGAT1FAAHRORC | |
| SCHEMBL10454523 | 0.82 | MAPT (0.54) | EPHX2FAAHCASP3TDP1POLB | |
| SCHEMBL10455653 | 0.80 | ELANE (0.45) | EPHX2ELANEDGAT1FAAHALDH1A1 | |
| SCHEMBL10454520 | 0.80 | ACSL1 (0.43) | ELANEACSL1KCNH2ALDH1A1LMNA | |
| SCHEMBL26857799 | 0.80 | AKR1C3 (0.51) | EPHX2DGAT1ACSL1ACSL3ACSL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0210772-B1 | 3-[(4-Aroyl)phenoxy(or phenylthio)]cyclopentanecarboxylic acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |