SCHEMBL10455652

SCHEMBL10455652

O=C(O)C(Cl)N(O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.43
ALDH1A1 P00352 4/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TP53 P04637 1/20 0.39
CYP2D6 P10635 1/20 0.38
SRC P12931 1/20 0.38
MAPK1 P28482 1/20 0.37
GLA P06280 1/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455650 1.00 NPSR1 (0.43) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL11342769 0.80 NPSR1 (0.44) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL4589661 0.77 SLC6A2 (0.43) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL449666 0.76 NPSR1 (0.44) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL449664 0.76 NPSR1 (0.44) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL4387218 0.74 ALDH1A1 (0.43) NPSR1ALDH1A1KMT2ALMNASMN1; SMN2
SCHEMBL4387215 0.74 ALDH1A1 (0.43) NPSR1ALDH1A1KMT2ALMNASMN1; SMN2
SCHEMBL11126728 0.74 LMNA (0.47) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL11324431 0.72 NPSR1 (0.37) NPSR1ALDH1A1HTTKMT2APOLB
SCHEMBL9283942 0.72 NPSR1 (0.41) NPSR1ALDH1A1HTTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0132349-B1 ANTIBIOTIC CALLED \"CHLOROPOLYSPORIN\", A PROCESS FOR ITS PREPARATION, AND ITS THERAPEUTIC AND VETERINARY USE SANKYO COMPANY LIMITED (JP) 1990-10-10 EP claimed
US-4557933-A Antibiotic called \"chloropolysporin\", a process for its preparation, and its therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1985-12-10 US claimed
EP-0132349-A2 Antibiotic called \"chloropolysporin\", a process for its preparation, and its therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1985-01-30 EP claimed
EP-0132349-B1 ANTIBIOTIC CALLED \"CHLOROPOLYSPORIN\", A PROCESS FOR ITS PREPARATION, AND ITS THERAPEUTIC AND VETERINARY USE SANKYO COMPANY LIMITED (JP) 1990-10-10 EP disclosed
US-4557933-A Antibiotic called \"chloropolysporin\", a process for its preparation, and its therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1985-12-10 US disclosed
EP-0132349-A2 Antibiotic called \"chloropolysporin\", a process for its preparation, and its therapeutic and veterinary use SANKYO COMPANY LIMITED (JP) 1985-01-30 EP disclosed