Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.36 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.35 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455806 | 0.82 | ELANE (0.45) | EPHX2NOTUMFAAH | |
| SCHEMBL10455809 | 0.77 | EPHX2 (0.43) | EPHX2DGAT1ACSL1ACSL3ACSL6 | |
| SCHEMBL11752125 | 0.75 | MAPT (0.48) | — | |
| SCHEMBL10454523 | 0.74 | MAPT (0.54) | EPHX2NOTUMFAAH | |
| SCHEMBL9279536 | 0.74 | MEN1 (0.55) | S1PR1 | |
| SCHEMBL10455781 | 0.73 | ELANE (0.57) | EPHX2DGAT1ACSL1ACSL3ACSL6 | |
| SCHEMBL10455484 | 0.73 | KMT2A (0.42) | EPHX2DGAT1NOTUMFAAH | |
| SCHEMBL10455517 | 0.73 | KMT2A (0.42) | EPHX2DGAT1NOTUMFAAH | |
| SCHEMBL26857799 | 0.72 | AKR1C3 (0.51) | EPHX2DGAT1ACSL1ACSL3ACSL6 | |
| SCHEMBL10454525 | 0.72 | KMT2A (0.53) | SRD5A1EPHX2DGAT1ACSL1ACSL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916147-A | 3-[(4-Aroyl) phenoxy (or phenylthio)]-cyclopentanecarboxylic acid analogues and treatment of cerebral edema therewith | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |