Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL7165382 | 1.00 | MAOB (0.70) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL13863540 | 0.95 | MAOB (0.64) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL14570386 | 0.95 | MAOB (0.64) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL17486896 | 0.93 | MAOB (0.67) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL14255742 | 0.93 | ALDH1A1 (0.62) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL17486897 | 0.91 | MAOB (0.64) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| (Z)-1,2-Diphenylethene SCHEMBL1877462 | 0.90 | HSD17B10 (0.67) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| Diphenylamine SCHEMBL7782610 | 0.87 | HSD17B10 (0.63) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL465277 | 0.85 | ALDH1A1 (0.65) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 | |
| SCHEMBL465276 | 0.85 | ALDH1A1 (0.65) | MAOBHSD17B10ALDH1A1MAPK1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897436-A | REACTION PRODUCT OF ISOPROPENYL PHENOLS OR BISPHENOLS WITH DIPHENYLAMINES OR PHENOTHIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| US-4754066-A | NITRILE RUBBERS, VULCANIZATES; REACTION PRODUCT OF MERCAPTO-CARBOXYLIC ACIDS AND 4-AMINODIPHENYLAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | disclosed |
| US-4654387-A | NITRILE RUBBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-31 | — | — | US | disclosed |