Diphenylamine

Diphenylamine

SCHEMBL7782610

C(=Cc1ccc(C=Cc2ccccc2)cc1)c1ccccc1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.63
ALDH1A1 P00352 3/20 0.60
ALOX12 P18054 2/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
ALOX15 P16050 1/20 0.60
TSHR P16473 1/20 0.60
PTGS1 P23219 1/20 0.60
SLC6A2 P23975 1/20 0.60
MAPK1 P28482 1/20 0.60
PTGS2 P35354 1/20 0.60
HTR2B P41595 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
MAOB P27338 3/20 0.54
MAOA P21397 2/20 0.54
NFE2L2 Q16236 1/20 0.54
CYP19A1 P11511 1/20 0.54
MAPT P10636 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
AR P10275 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465276 0.97 ALDH1A1 (0.65) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL465277 0.97 ALDH1A1 (0.65) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
(Z)-1,2-Diphenylethene SCHEMBL1877462 0.97 HSD17B10 (0.67) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL3372676 0.95 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL3374038 0.95 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL293235 0.95 ALDH1A1 (0.60) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
SCHEMBL10042620 0.95 ALDH1A1 (0.60) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
Diphenylamine SCHEMBL4735870 0.93 HSD17B10 (0.55) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
Diphenylamine SCHEMBL10827517 0.89 MAPT (0.52) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15
Diphenylamine SCHEMBL10865540 0.89 HPGD (0.68) HSD17B10ALDH1A1ALOX12L3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1136871-A2 Colour liquid crystal display device Philips Patentverwaltung GmbH (DE) 2001-09-26 EP disclosed
US-5250377-A Durable, highly photosensitive RICOH COMPANY, LTD. (JP) 1993-10-05 US disclosed
US-5159087-A High photosensitivity, durability RICOH COMPANY, LTD. (JP) 1992-10-27 US disclosed
US-4886846-A CHARGE TRANSFER COMPOUNDS RICOH COMPANY, LTD. (JP) 1989-12-12 US disclosed