Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.59 |
| ▸ | CA6 | P23280 | 5/20 | 0.59 |
| ▸ | CA7 | P43166 | 5/20 | 0.59 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA4 | P22748 | 4/20 | 0.59 |
| ▸ | CA5A | P35218 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | F13A1 | P00488 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
| ▸ | CASP2 | P42575 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CA3 | P07451 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456364 | 0.98 | CA12 (0.56) | CA12CA6CA7CA9CA14 | |
| SCHEMBL10456366 | 0.93 | CA12 (0.54) | CA12CA6CA7CA9CA14 | |
| SCHEMBL2479651 | 0.88 | — | — | |
| SCHEMBL1188399 | 0.81 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL947067 | 0.79 | CASP2 (0.36) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL28990888 | 0.78 | CA12 (0.68) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5501507 | 0.77 | CA12 (0.39) | CA12CA6CA7CA9CA14 | |
| SCHEMBL17740072 | 0.77 | GNAI3 (0.41) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL288720 | 0.77 | CA12 (1.00) | CA12CA6CA7CA9CA14 | |
| Spermine SCHEMBL8514287 | 0.77 | CA12 (1.00) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039325-A | Use of Bruton's Tyrosine Kinase (BTK) inhibitors | PHARMACYCLICS INC | 2014-09-10 | — | — | CN | disclosed |
| CN-1780850-A | Use of lectins to promote oligomerization of glycoproteins and antigenic molecules | ANTIGENICS INC (US) | 2006-05-31 | — | — | CN | disclosed |
| US-4925835-A | INHIBITING PROLIFERATION OF CANCER CELLS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |