SCHEMBL10456743

SCHEMBL10456743

CCCOC1(OCCC)C=CC(C(=O)c2ccccc2O)=C(O)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 5/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C19 P33261 2/20 0.35
PGR P06401 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CHRM1 P11229 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
TBXA2R P21731 1/20 0.35
SLC6A2 P23975 1/20 0.35
ADRA1A P35348 1/20 0.35
HIF1A Q16665 1/20 0.35
TSHR P16473 2/20 0.34
NAAA Q02083 1/20 0.33
LIG1 P18858 1/20 0.33
KMT2A Q03164 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10632342 0.93 TSHR (0.39) ALDH1A1TDP1LMNACYP1A2CYP3A4
SCHEMBL29092707 0.91 ALDH1A1 (0.32) ALDH1A1TDP1LMNACYP1A2CYP3A4
SCHEMBL11075484 0.90 TSHR (0.36) ALDH1A1TDP1LMNACYP1A2CYP3A4
SCHEMBL11045875 0.88 TSHR (0.36) ALDH1A1TDP1LMNACYP1A2CYP3A4
SCHEMBL29222803 0.85 LMNA (0.35) ALDH1A1TDP1LMNACYP1A2CYP3A4
SCHEMBL30729261 0.82 LMNA (0.41) ALDH1A1TDP1LMNACYP1A2CYP3A4
SCHEMBL10615105 0.82 LMNA (0.38) ALDH1A1LMNAHPGDKMT2AL3MBTL1
SCHEMBL28435555 0.81 LMNA (0.37) ALDH1A1TDP1LMNACYP1A2CYP2C19
SCHEMBL28438096 0.80 LMNA (0.38) ALDH1A1LMNACYP1A2CYP3A4CYP2C19
SCHEMBL28694799 0.78 LMNA (0.35) ALDH1A1TDP1LMNACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502333-B organic resin laminate EXATEC, LLC (US) 2016-05-04 CN disclosed
CN-103732337-A Organic resin laminate, methods of making and using the same, and articles comprising the same EXATEC LLC 2014-04-16 CN disclosed
CN-103502333-A Organic resin laminate EXATEC LLC 2014-01-08 CN disclosed
US-4902724-A Photocurable acrylic coating composition GENERAL ELECTRIC COMPANY (US) 1990-02-20 US disclosed
EP-0274595-A2 Aromatic carbonate resin articles coated with a photocured acrylic coating GENERAL ELECTRIC COMPANY (US) 1988-07-20 EP disclosed
EP-0274596-A2 Aromatic carbonate resin articles coated with a photocured acrylic coating GENERAL ELECTRIC COMPANY (US) 1988-07-20 EP disclosed