SCHEMBL11075484

SCHEMBL11075484

CCCCOC1(OCC)C=CC(C(=O)c2ccccc2O)=C(O)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.36
TDP1 Q9NUW8 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NAAA Q02083 1/20 0.35
LMNA P02545 5/20 0.34
CYP3A4 P08684 3/20 0.34
CYP1A2 P05177 1/20 0.34
PGR P06401 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
AR P10275 1/20 0.34
CHRM1 P11229 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
TBXA2R P21731 1/20 0.34
SLC6A2 P23975 1/20 0.34
CYP2C19 P33261 1/20 0.34
ADRA1A P35348 1/20 0.34
HIF1A Q16665 1/20 0.34
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10632342 0.97 TSHR (0.39) TSHRTDP1L3MBTL1NAAALMNA
SCHEMBL11045875 0.91 TSHR (0.36) TSHRTDP1L3MBTL1NAAALMNA
SCHEMBL10456743 0.90 ALDH1A1 (0.36) TSHRTDP1L3MBTL1NAAALMNA
SCHEMBL29222803 0.89 LMNA (0.35) TSHRTDP1L3MBTL1NAAALMNA
SCHEMBL28441472 0.87 LMNA (0.34) TSHRTDP1L3MBTL1LMNAHPGD
SCHEMBL9726078 0.86 LMNA (0.43) TSHRTDP1L3MBTL1LMNACYP3A4
SCHEMBL28694799 0.83 LMNA (0.35) TSHRTDP1L3MBTL1LMNACYP1A2
SCHEMBL29092707 0.82 ALDH1A1 (0.32) TSHRTDP1NAAALMNACYP3A4
SCHEMBL28435555 0.81 LMNA (0.37) TSHRTDP1L3MBTL1LMNACYP1A2
SCHEMBL10615105 0.80 LMNA (0.38) L3MBTL1LMNAHPGDALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0107654-A4 COATED SURFACE STABILIZED POLYCARBONATE ARTICLE. GEN ELECTRIC (US) 1984-08-10 EP disclosed
EP-0107654-A1 COATED SURFACE STABILIZED POLYCARBONATE ARTICLE. GEN ELECTRIC (US) 1984-05-09 EP disclosed
WO-1983003905-A1 COATED SURFACE STABILIZED POLYCARBONATE ARTICLE GENERAL ELECTRIC COMPANY (US) 1983-11-10 WO disclosed