SCHEMBL10457366

SCHEMBL10457366

CCO[Si](OCC)(OCC(C)C)OCC(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28964503 1.00 ALDH1A1 (0.31) ALDH1A1LMNA
SCHEMBL200595 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL29217396 0.79 HSD17B10 (0.36)
SCHEMBL452809 0.78
SCHEMBL17680 0.78
SCHEMBL8681223 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1323866 0.76
SCHEMBL11204788 0.76
SCHEMBL16222843 0.76 THRB (0.30)
SCHEMBL11207330 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406540-B Procatalyst for polymerization of olefins SABIC环球技术有限责任公司 2020-04-17 CN disclosed
US-4942148-A COORDINATION CATALYLTS OF METAL OXIDE, ORGANOMAGNESIUM COMPOUNDS, AN ORGANOALUMINUM COMPOUND, A TITANIUM COMPOUND AND ELECTRON DONOR COMPOUND TOA NENRYO KOGYO, K.K. (JP) 1990-07-17 US disclosed
EP-0312314-A1 Catalyst component for olefin polymerization Tonen Corporation (JP) 1989-04-19 EP disclosed