SCHEMBL10458014

SCHEMBL10458014

CCc1ccc2ccc(C(C)=O)cc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.59
CYP1A2 P05177 1/20 0.52
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
MAPT P10636 1/20 0.47
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
PLK1 P53350 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
F2 P00734 1/20 0.42
PLG P00747 1/20 0.42
PLAU P00749 1/20 0.42
PLAT P00750 1/20 0.42
KLKB1 P03952 1/20 0.42
PRSS1 P07477 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803029 0.94 CYP2A6 (0.53) CYP2A6CYP1A2KMT2AALDH1A1HPGD
SCHEMBL599006 0.84 CYP2A6 (0.79) CYP2A6KMT2AALDH1A1HPGDMAPT
SCHEMBL29451111 0.84 CYP2A6 (0.79) CYP2A6KMT2AALDH1A1HPGDMAPT
SCHEMBL10457821 0.84 CYP1A2 (0.50) CYP2A6CYP1A2KMT2AALDH1A1HPGD
SCHEMBL11741237 0.82 CYP2A6 (0.56) CYP2A6KMT2AALDH1A1HPGDMAPT
SCHEMBL5034583 0.81 CYP2A6 (0.52) CYP2A6CYP1A2ALDH1A1HPGDAKR1C3
SCHEMBL10306521 0.81 KMT2A (0.63) CYP2A6CYP1A2KMT2AALDH1A1HPGD
SCHEMBL10458080 0.81 CYP2A6 (0.47) CYP2A6CYP1A2ALDH1A1HPGDAKR1C3
SCHEMBL10457997 0.81 AKR1C3 (0.50) CYP2A6CYP1A2ALDH1A1MAPTAKR1C3
SCHEMBL29475635 0.79 CYP2A6 (0.76) CYP2A6CYP1A2KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935537-A OXIDIZING ACYLALKYLNAPHTHALENE WITH PEROXIDE, OXIDIZING PRODUCT WITH OXYGEN USING CATALYST CONTAINING COBALT AND BROMINE COMPOUNDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-06-19 US disclosed
US-4801737-A Process for producing acyloxynaphthoic acids MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-01-31 US disclosed
EP-0170273-B1 PROCESS FOR PRODUCING ACYLOXYNAPHTHOIC ACIDS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1988-12-28 EP disclosed
EP-0170273-A2 Process for producing acyloxynaphthoic acids MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1986-02-05 EP disclosed