Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479651 | 0.87 | — | — | |
| SCHEMBL13496721 | 0.81 | ACE2 (0.44) | ACE2SIGMAR1ALOX15KEAP1SMN1; SMN2 | |
| SCHEMBL1615517 | 0.80 | ALOX15 (0.61) | ACE2SIGMAR1ALOX15KEAP1SMN1; SMN2 | |
| SCHEMBL4666999 | 0.80 | — | — | |
| SCHEMBL10456366 | 0.79 | CA12 (0.54) | ACE2ALOX15SMN1; SMN2 | |
| SCHEMBL29263862 | 0.78 | GNAI3 (0.54) | ACE2ALOX15 | |
| SCHEMBL1615521 | 0.78 | ALOX15 (0.58) | ACE2SIGMAR1ALOX15KEAP1SMN1; SMN2 | |
| SCHEMBL1614410 | 0.78 | ALOX15 (0.58) | ACE2SIGMAR1ALOX15KEAP1SMN1; SMN2 | |
| SCHEMBL1614431 | 0.78 | ALOX15 (0.58) | ACE2SIGMAR1ALOX15KEAP1SMN1; SMN2 | |
| SCHEMBL1615232 | 0.78 | ALOX15 (0.58) | ACE2SIGMAR1ALOX15KEAP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925835-A | INHIBITING PROLIFERATION OF CANCER CELLS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |