Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.53 |
| ▸ | ESR1 | P03372 | 7/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811720 | 0.84 | CNR1 (0.50) | ESR2ESR1HSD17B1HCAR2SHBG | |
| SCHEMBL4457614 | 0.82 | HSD17B1 (0.49) | ESR2ESR1HSD17B1HCAR2RARB | |
| SCHEMBL29738442 | 0.81 | ESR2 (0.76) | ESR2ESR1HSD17B1FGFR1HSD17B10 | |
| SCHEMBL439874 | 0.81 | ESR2 (0.76) | ESR2ESR1HSD17B1FGFR1HSD17B10 | |
| SCHEMBL4935609 | 0.81 | DGAT1 (0.57) | ESR2HSD17B1HCAR2RARBHSD17B10 | |
| SCHEMBL1678974 | 0.81 | MMP3 (0.55) | ESR2ESR1HSD17B1HCAR2 | |
| SCHEMBL16941050 | 0.81 | PTGS1 (0.46) | ESR2ESR1RARB | |
| SCHEMBL19722630 | 0.80 | RARB (0.60) | ESR2ESR1SHBGRARBHSD17B10 | |
| SCHEMBL2718119 | 0.79 | ESR2 (0.73) | ESR2ESR1HSD17B1FGFR1HSD17B10 | |
| SCHEMBL23453183 | 0.79 | CYP3A4 (0.52) | ESR2ESR1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247357-B1 | IMPACT RESISTANT RESIN COMPOSITION | UNITIKA LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |
| US-4804707-A | BLEND OF POLYARYLATE, POLYAMIDE WITH EPOXY GROUP-CONTAINING OLEFIN POLYMER AND ACID ANHYDRIDE CONTAINING OLOEFIN POLYMER | UNITIKA LTD. (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0247357-A1 | Impact resistant resin composition | UNITIKA LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |