Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | TK2 | O00142 | 2/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744350 | 0.92 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL9747028 | 0.91 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3185225 | 0.91 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3179329 | 0.91 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL2419477 | 0.91 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3183300 | 0.91 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL10428773 | 0.91 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL9821380 | 0.89 | LMNA (0.41) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL9821197 | 0.89 | LMNA (0.43) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL11020536 | 0.86 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916121-A | PHOSPHORYLASE INHIBITOR | TEIJIN LIMITED (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0202056-B1 | ANTITUMOR AGENT | TEIJIN LIMITED (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0202056-A1 | Antitumor agent | TEIJIN LIMITED (JP) | 1986-11-20 | — | — | EP | disclosed |