Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022379 | 1.00 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3179329 | 0.92 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3185225 | 0.92 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL2419477 | 0.92 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL3183300 | 0.92 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL10428773 | 0.92 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL9747028 | 0.92 | LMNA (0.39) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL9821380 | 0.92 | LMNA (0.41) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL9744350 | 0.91 | LMNA (0.40) | LMNASMN1; SMN2MAPTESR1TSHR | |
| SCHEMBL10458148 | 0.86 | LMNA (0.41) | LMNASMN1; SMN2MAPTESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151189-A1 | ANTINEOPLASTIC AGENT | TEIJIN LIMITED (JP) | 1985-08-14 | — | — | EP | disclosed |