Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TK2 | O00142 | 3/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428773 | 1.00 | LMNA (0.39) | LMNASMN1; SMN2TK2SQORCYP3A4 | |
| SCHEMBL3185225 | 1.00 | LMNA (0.39) | LMNASMN1; SMN2TK2SQORCYP3A4 | |
| SCHEMBL3179329 | 1.00 | LMNA (0.39) | LMNASMN1; SMN2TK2SQORCYP3A4 | |
| SCHEMBL3183300 | 1.00 | LMNA (0.39) | LMNASMN1; SMN2TK2SQORCYP3A4 | |
| SCHEMBL9747028 | 1.00 | LMNA (0.39) | LMNASMN1; SMN2TK2SQORCYP3A4 | |
| SCHEMBL9744350 | 0.99 | LMNA (0.40) | LMNASMN1; SMN2TK2SQORCYP3A4 | |
| SCHEMBL11020536 | 0.92 | LMNA (0.40) | LMNASMN1; SMN2TK2MAPTESR1 | |
| SCHEMBL11022379 | 0.92 | LMNA (0.40) | LMNASMN1; SMN2TK2MAPTESR1 | |
| SCHEMBL10458148 | 0.91 | LMNA (0.41) | LMNASMN1; SMN2TK2MAPTESR1 | |
| SCHEMBL9745084 | 0.90 | SQOR (0.44) | SMN1; SMN2TK2SQORASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133087-A1 | ASSAY OF CYTOKINES ASSOCIATED WITH MSRV/HERV-W | bioMérieux (FR) | 2017-02-22 | — | — | EP | disclosed |
| EP-1709082-B1 | COMPOSITION FOR TREATING PATHOLOGY ASSOCIATED WITH MSRV/HERV-W | BIOMERIEUX SA (FR) | 2014-03-12 | — | — | EP | disclosed |
| EP-2365002-A2 | Composition for treating a pathology associated with MSRV/HERV-W | bioMérieux (FR) | 2011-09-14 | — | — | EP | disclosed |
| US-7666420-B2 | Composition for treating pathology associated with MSRV/HERV-W | BIOMERIEUX (FR) | 2010-02-23 | — | — | US | disclosed |
| US-20080038279-A1 | Composition For Treating Pathology Associated With Msrv/Herv-W | BIOMERIEUX (FR) | 2008-02-14 | — | — | US | disclosed |
| EP-0227844-B1 | ANTIVIRAL DRUG | TEIJIN LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0214299-B1 | PREPARATION OF 5-FLUORO-2'-DEOXYURIDINE ESTERS FOR INTRAARTERIAL ADMINISTRATION | TEIJIN LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-5013828-A | Fluorinating 2'-deoxyuridine with fluorine gas, fatty acid salt present, acylation with acid anhydride or halide | CENTRAL GLASS COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| US-4943564-A | Intraarterial injection pharmaceuticals of 5-fluoro-2'-deoxyuridine esters | TEIJIN LIMITED (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4868162-A | 5-HALO-2*-DEOXYURIDINE DERIVATIVE | TEIJIN LIMITED (JP) | 1989-09-19 | — | — | US | disclosed |
| US-4757139-A | 5-fluoro-2'-deoxyuridine derivative, processes for preparing same and antitumor composition containing the same | TEIJIN LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0227844-A1 | ANTIVIRAL DRUG | TEIJIN LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0214299-A1 | PREPARATION OF 5-FLUORO-2'-DEOXYURIDINE ESTERS FOR INTRAARTERIAL ADMINISTRATION | TEIJIN LIMITED (JP) | 1987-03-18 | — | — | EP | disclosed |
| EP-0151189-A1 | ANTINEOPLASTIC AGENT | TEIJIN LIMITED (JP) | 1985-08-14 | — | — | EP | disclosed |