Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145950 | 0.85 | HAO1 (0.51) | HAO1HDAC8HDAC6HDAC1BCL2L1 | |
| SCHEMBL16790349 | 0.79 | HAO1 (0.43) | HAO1HDAC8HDAC6HDAC1BCL2L1 | |
| SCHEMBL9390752 | 0.78 | ALDH1A1 (0.60) | HAO1HDAC8HDAC6HDAC1CYP2C9 | |
| SCHEMBL27928265 | 0.78 | HAO1 (0.50) | HAO1HDAC8HDAC6HDAC1BCL2L1 | |
| SCHEMBL9667339 | 0.77 | HDAC8 (0.54) | HAO1HDAC8HDAC6HDAC1BCL2L1 | |
| SCHEMBL11457122 | 0.77 | ALDH1A1 (0.59) | HAO1HDAC8HDAC6HDAC1ALDH1A1 | |
| SCHEMBL9395478 | 0.76 | ALDH1A1 (0.60) | MMP2MMP3ALDH1A1 | |
| SCHEMBL27772232 | 0.75 | HDAC8 (0.53) | HAO1HDAC8HDAC6HDAC1BCL2L1 | |
| SCHEMBL29003564 | 0.75 | HDAC8 (0.56) | HAO1HDAC8HDAC6HDAC1BCL2L1 | |
| SCHEMBL9338809 | 0.74 | ALDH1A1 (0.61) | CYP2C9ALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902725-A | Photocurable acrylic coating composition | GENERAL ELECTRIC COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| EP-0274595-A2 | Aromatic carbonate resin articles coated with a photocured acrylic coating | GENERAL ELECTRIC COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |