Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429788 | 0.88 | APP (1.00) | APPMAPTALDH1A1MAOBNPC1 | |
| SCHEMBL18429716 | 0.88 | APP (1.00) | APPMAPTALDH1A1MAOBNPC1 | |
| SCHEMBL10457449 | 0.87 | APP (0.59) | APPCA12CA1CA9ALDH1A1 | |
| SCHEMBL10980310 | 0.87 | APP (0.83) | APPCA1CA2MAOBNPC1 | |
| SCHEMBL1343630 | 0.85 | CA12 (0.65) | APPMAPTCA12CA1CA2 | |
| SCHEMBL8434882 | 0.82 | CA12 (0.61) | APPMAPTCA12CA1CA2 | |
| SCHEMBL9808262 | 0.82 | MAPT (0.62) | APPMAPTCA12CA1CA2 | |
| SCHEMBL77535 | 0.81 | ALDH1A1 (0.60) | APPMAPTCA12CA1CA2 | |
| SCHEMBL8274286 | 0.81 | L3MBTL1 (0.59) | APPALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL2628228 | 0.81 | L3MBTL1 (0.59) | APPALDH1A1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |