Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764935 | 0.89 | CHRNB2 (0.57) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL29510932 | 0.87 | CHRNB2 (0.69) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL1470185 | 0.87 | CHRNB2 (0.69) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL238984 | 0.86 | CHRNB2 (0.62) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL7089196 | 0.85 | CHRNB2 (0.67) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL11231915 | 0.85 | CHRNB2 (0.67) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL5961821 | 0.85 | KCNH2 (0.50) | DRD2DRD4DRD3APPKCNH2 | |
| SCHEMBL24263031 | 0.84 | CHRNB2 (0.61) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL9502826 | 0.84 | CHRNB2 (0.61) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL16902832 | 0.83 | CHRNB2 (0.65) | CHRNB2CHRNA4DRD2DRD4ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4552894-A | INSECTICIDE, MITICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-11-12 | — | — | US | disclosed |