Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1436655 | 0.98 | CHRNB2 (0.59) | CHRNB2CHRNA4TAAR1DRD2DRD4 | |
| SCHEMBL20978768 | 0.90 | CHRNB2 (0.59) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL3735506 | 0.89 | CHRNB2 (0.57) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL1470185 | 0.87 | CHRNB2 (0.69) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL29510932 | 0.87 | CHRNB2 (0.69) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL8916326 | 0.87 | CHRNB2 (0.56) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL8765012 | 0.87 | CHRNB2 (0.56) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL11231915 | 0.85 | CHRNB2 (0.67) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL7089196 | 0.85 | CHRNB2 (0.67) | CHRNB2CHRNA4DRD2DRD4ADRA1D | |
| SCHEMBL9107098 | 0.85 | TAAR1 (0.70) | TAAR1LTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031941-A1 | HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS | NOXELL CORPORATION (US) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017189595-A1 | HAIR TREATMENT METHOD AND KIT THEREOF | NOXELL CORPORATION (US) | 2017-11-02 | — | — | WO | disclosed |
| WO-2017189601-A1 | HAIR TREATMENT METHOD AND KIT THEREOF | NOXELL CORPORATION (US) | 2017-11-02 | — | — | WO | disclosed |
| EP-2828238-B1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | ADAMED SP ZOO (PL) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015095052-A1 | ISOINDOLIN-1-ONES AS MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) INHIBITORS | CONTROLLED CHEMICALS, INC. (US) | 2015-06-25 | — | — | WO | disclosed |
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | ADAMED SP. ZO.O (PL) | 2015-02-19 | — | — | US | disclosed |
| EP-2828238-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | Adamed Sp. z o.o. (PL) | 2015-01-28 | — | — | EP | disclosed |
| CN-104220421-A | Sulfonamide derivatives of benzylamine for the treatment of central nervous system disorders | ADAMED SP ZOO | 2014-12-17 | — | — | CN | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2013140347-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | ADAMED SP. Z O.O. (PL) | 2013-09-26 | — | — | WO | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| EP-0548307-A1 | PROCESS FOR THE OXIDATIVE COLOURING OF HAIR | Wella Aktiengesellschaft (DE) | 1993-06-30 | — | — | EP | disclosed |
| WO-1993001792-A1 | PROCESS FOR THE OXIDATIVE COLOURING OF HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 1993-02-04 | — | — | WO | disclosed |
| WO-1983001771-A1 | DERIVATIVES OF 2-HYDROXY-4-AMINO-BENZENE, PREPARATION THEREOF AND HAIR DYE CONTAINING SUCH DERIVATIVES | KONRAD, EUGEN | 1983-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051257-A1 | SULPHONAMIDE DERIVATIVES OF BENZYLAMINE FOR THE TREATMENT OF CNS DISEASES | AQP4, BCL6, STS | CHRNB2 469/4885CHRNA4 227/4885TAAR1 861/4885 |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | CBR3, CBR1, AKR1C4 | CHRNB2 1666/4885CHRNA4 1046/4885TAAR1 1564/4885 |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | PIR, PFAS, PNPO | CHRNB2 4265/4885CHRNA4 4027/4885TAAR1 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.