SCHEMBL5961821

SCHEMBL5961821

FCCOc1cccc(OCCF)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.50
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 2/20 0.44
TAAR1 Q96RJ0 1/20 0.44
RECQL P46063 1/20 0.44
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44
KCNA3 P22001 1/20 0.44
PRSS1 P07477 2/20 0.42
APP P05067 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10456734 0.89 MAPK1 (0.61) MAPK1ALDH1A1RECQLAPPCYP3A4
SCHEMBL5961833 0.88 KCNA3 (0.48) MAPK1TAAR1KCNA3PRSS1TSHR
SCHEMBL10457904 0.88 KDM4E (0.54) KCNH2MAPK1ALDH1A1TSHRSMN1; SMN2
SCHEMBL4857175 0.87 MAOB (0.46) KCNH2
SCHEMBL10458205 0.86 MEN1 (0.44) KCNH2MAPK1ALDH1A1TSHRSMN1; SMN2
SCHEMBL10458635 0.85 KCNH2 (0.44) KCNH2CA12CA1CA9DRD2
SCHEMBL900772 0.85 MAOB (0.56) ALDH1A1
SCHEMBL10458289 0.85 LMNA (0.59) KCNH2MAPK1DRD2DRD4DRD3
SCHEMBL30567997 0.85 MAOB (0.56) ALDH1A1
SCHEMBL10458235 0.85 CHRNB2 (0.61) KCNH2DRD2DRD4DRD3APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4960884-A Insecticides, nematocides, pesticides and miticides FMC CORPORATION (US) 1990-10-02 US claimed
US-7074523-B2 Lithium secondary battery HITACHI, LTD. (JP) 2006-07-11 US disclosed
US-20040106039-A1 nonaqueous electrolytic solution containing a compound that is oxidized at a voltage > a charge end voltage of the battery and a compound which inhibits reactions at voltages < the charge end voltage ARAI JUICHI (JP) 2004-06-03 US disclosed
US-20030003370-A1 Nonaqueous electrolytic solution containing a compound which is oxidized at a voltage higher than a charge end voltage of the lithium secondary battery and a compound which inhibits reactions at voltages lower than said charge end voltage. HITACHI, LTD. (JP) 2003-01-02 US disclosed
EP-1258939-A2 Lithium secondary battery Hitachi, Ltd. (JP) 2002-11-20 EP disclosed