Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388680 | 0.85 | THRB (0.52) | THRBGAATSHRHPGDMAPT | |
| SCHEMBL1111483 | 0.84 | ALDH1A1 (0.45) | TDP1THRBGAATSHRHPGD | |
| SCHEMBL10925796 | 0.83 | KDM4E (0.49) | GAATSHRLMNAALDH1A1KDM4E | |
| SCHEMBL10507951 | 0.82 | GAA (0.41) | GAATSHRMAPTKDM4ENPC1 | |
| SCHEMBL10455714 | 0.81 | GAA (0.53) | THRBGAATSHRMAPTHTT | |
| SCHEMBL10846802 | 0.80 | GCK (0.46) | GAATSHRMAPTLMNAHTT | |
| SCHEMBL10743535 | 0.80 | GAA (0.45) | TDP1GAATSHRMAPTALDH1A1 | |
| SCHEMBL10927440 | 0.80 | MEN1 (0.42) | TDP1THRBGAAALDH1A1 | |
| SCHEMBL10917299 | 0.79 | KMT2A (0.46) | TDP1THRBGAATSHRMAPT | |
| SCHEMBL10695861 | 0.79 | ALDH1A1 (0.48) | THRBGAATSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978383-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |
| US-4835311-A | N-phenylsulfonyl-N'-pyrimidinyl- and -N'-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1989-05-30 | — | — | US | disclosed |
| US-4739068-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | disclosed |
| US-4726836-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4648899-A | N-phenylsulfonyl-N'-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4618363-A | N-phenylsulfonyl-N'-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |