Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848909 | 0.92 | GAA (0.52) | GCKCASP1GAAMAPTHTT | |
| SCHEMBL10994772 | 0.87 | RAB9A (0.49) | GCKCASP1LMNAIDH1MAPT | |
| SCHEMBL10388680 | 0.87 | THRB (0.52) | LMNAGAAMAPTHTTTSHR | |
| SCHEMBL11002896 | 0.85 | MAPT (0.47) | CASP1GAAMAPTKDM4ENPC1 | |
| SCHEMBL10999376 | 0.84 | MAPT (0.44) | GCKCASP1GAAIDH1MAPT | |
| SCHEMBL11201513 | 0.84 | GCK (0.45) | GCKCASP1IDH1KDM4ENPC1 | |
| SCHEMBL10994300 | 0.84 | ALDH1A1 (0.41) | GCKCASP1LMNAALDH1A1TSHR | |
| SCHEMBL10994307 | 0.84 | ALDH1A1 (0.41) | GCKCASP1LMNAALDH1A1TSHR | |
| SCHEMBL11062373 | 0.83 | LMNA (0.47) | LMNAMAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL10695861 | 0.83 | ALDH1A1 (0.48) | LMNAGAAIDH1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602941-A | Herbicidally active novel substituted phenylsulfonylurea derivatives and new intermediates therefor | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-29 | — | — | US | claimed |