SCHEMBL9036644

SCHEMBL9036644

NNC(=O)Nc1ccccc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.68
KDM4E B2RXH2 4/20 0.64
MAPT P10636 5/20 0.61
LMNA P02545 4/20 0.61
ALDH1A1 P00352 2/20 0.61
MEN1 O00255 6/20 0.57
KMT2A Q03164 6/20 0.57
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
POLB P06746 2/20 0.57
GAA P10253 2/20 0.57
MAPK1 P28482 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
CASP3 P42574 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
HTT P42858 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5119113 0.98 CYP1A2 (0.66) CYP1A2KDM4EMAPTLMNAALDH1A1
SCHEMBL10458447 0.87 KDM4E (0.72) CYP1A2KDM4EMAPTLMNAALDH1A1
SCHEMBL9168941 0.82 MAPT (0.59) CYP1A2KDM4EMAPTLMNAALDH1A1
SCHEMBL19006812 0.82 KDM4E (0.66) KDM4EMAPTLMNAALDH1A1MEN1
SCHEMBL11449284 0.82 CYP1A2 (0.65) CYP1A2KDM4EMAPTLMNAALDH1A1
SCHEMBL2175829 0.81 CYP1A2 (0.75) CYP1A2KDM4EMAPTLMNAALDH1A1
SCHEMBL29537172 0.81 CYP1A2 (0.75) CYP1A2KDM4EMAPTLMNAALDH1A1
Hydrochloric Acid SCHEMBL9630506 0.80 KDM4E (0.64) KDM4EMAPTLMNAALDH1A1MEN1
SCHEMBL8830517 0.80 SMN1; SMN2 (0.73) CYP1A2KDM4EMAPTLMNAALDH1A1
SCHEMBL8421117 0.80 CYP1A2 (0.62) CYP1A2KDM4EMAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
WO-2021127459-A1 GPR139 RECEPTOR MODULATORS BLACKTHORN THERAPEUTICS, INC. (US) 2021-06-24 WO disclosed
WO-2021127459-A1 GPR139 RECEPTOR MODULATORS BLACKTHORN THERAPEUTICS, INC. (US) 2021-06-24 WO disclosed
EP-0566445-B1 Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy INNOTHERA LAB SA (FR) 1996-02-07 EP disclosed
EP-0474817-B1 BICYCLO [3.3.0]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE SCHERING AG (DE) 1995-10-11 EP disclosed
EP-0566445-A1 Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy INNOTHERA (FR) 1993-10-20 EP disclosed
WO-1993020045-A1 INDAN-1,3-DIONE AND INDAN-1,2,3-TRIONE DERIVATIVES, PROCESSES FOR THE PREPARATION OF SAME AND THEIR APPLICATION AS THERAPEUTIC AGENTS INNOTHERA (FR) 1993-10-14 WO disclosed
EP-0474817-A1 BICYCLO 3.3.)]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE. SCHERING AG (DE) 1992-03-18 EP disclosed
WO-1991014675-A1 BICYCLO[3.3.)]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1991-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT CYP1A2 313/4885KDM4E 2549/4885MAPT 2002/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT CYP1A2 313/4885KDM4E 2549/4885MAPT 2002/4885
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT CYP1A2 313/4885KDM4E 2549/4885MAPT 2002/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT CYP1A2 313/4885KDM4E 2549/4885MAPT 2002/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT CYP1A2 313/4885KDM4E 2549/4885MAPT 2002/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT CYP1A2 313/4885KDM4E 2549/4885MAPT 2002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.