SCHEMBL10458489

SCHEMBL10458489

Brc1ccc2c(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c3ccccc3c(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
HDAC4 P56524 1/20 0.39
KMT2A Q03164 2/20 0.37
TSPO P30536 1/20 0.35
ALDH1A1 P00352 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
DPP4 P27487 1/20 0.34
PTGS2 P35354 2/20 0.33
MAPK8 P45983 2/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
ACHE P22303 1/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.33
RAD52 P43351 1/20 0.33
EDNRB P24530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1714949 0.91 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL12571778 0.87 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL13615689 0.87 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL30040723 0.85 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL26218475 0.85 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL14913074 0.85 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL12700855 0.85 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2ATSPO
SCHEMBL275300 0.85 L3MBTL1 (0.64) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL29805203 0.83 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL28651934 0.83 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991514-B1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2017-12-20 EP disclosed
US-8318325-B2 Anthracene derivatives and organic electronic device using same LG CHEM, LTD. (KR) 2012-11-27 US disclosed
US-8318325-B2 Anthracene derivatives and organic electronic device using same LG CHEM, LTD. (KR) 2012-11-27 US disclosed
US-8222634-B2 Anthracene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-07-17 US disclosed
US-8222634-B2 Anthracene derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2012-07-17 US disclosed
US-20110156017-A1 NOVEL ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2011-06-30 US disclosed
US-20110156017-A1 NOVEL ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2011-06-30 US disclosed
US-7965032-B2 Anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2011-06-21 US disclosed
US-7965032-B2 Anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2011-06-21 US disclosed
US-20110024725-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-02-03 US disclosed
US-20110024725-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-02-03 US disclosed
WO-2007102683-A9 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2008-12-24 WO disclosed
WO-2008143440-A1 NEW ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-11-27 WO disclosed
WO-2007102683-A1 NOVEL ANTHRACENE DERIVATIVE AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2007-09-13 WO disclosed
US-20070205412-A1 Novel anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2007-09-06 US disclosed
US-20070205412-A1 Novel anthracene derivative and organic electronic device using the same LG CHEM, LTD. (KR) 2007-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110156017-A1 NOVEL ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING SAME VDAC2, VDAC3, ANXA1 L3MBTL1 3330/4885KDM4E 542/4885ATM 1025/4885
US-20110024725-A1 ANTHRACENE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC3, ANXA1 L3MBTL1 3721/4885KDM4E 543/4885ATM 1058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.