SCHEMBL1714949

SCHEMBL1714949

Brc1ccc2c(c1)c1ccccc1n2-c1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.49
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
KMT2A Q03164 3/20 0.41
HDAC4 P56524 1/20 0.40
TSPO P30536 2/20 0.39
PTGS2 P35354 2/20 0.37
MEN1 O00255 2/20 0.37
RAD52 P43351 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 1/20 0.36
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
IL1R1 P14778 1/20 0.35
RXFP1 Q9HBX9 2/20 0.35
DCLK1 O15075 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560455 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL29976044 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL25672222 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL30844030 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL10458489 0.91 L3MBTL1 (0.47) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL13299350 0.91 DCLK1 (0.41) L3MBTL1KDM4EATMKMT2APTGS2
SCHEMBL30040723 0.89 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL14913074 0.89 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL26218475 0.89 L3MBTL1 (0.52) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL19152369 0.88 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330097-B1 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2013-01-23 EP claimed
EP-2330097-A1 Carbazole derivative and method for producing the same Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-06-08 EP claimed
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-20140187791-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-03 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
US-8669373-B2 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-11 US disclosed
EP-2330097-B1 Carbazole derivative and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2013-01-23 EP disclosed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
EP-2166001-B1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-25 US disclosed
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-25 US disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
EP-2166001-A1 Carbazole Derivative and Method for Producing the Same Semiconductor Energy Laboratory Co., Ltd. (JP) 2010-03-24 EP disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-18 US disclosed
WO-2010005066-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL, LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed
WO-2010005066-A1 CARBAZOLE DERIVATIVE, LIGHT-EMITTING ELEMENT MATERIAL, LIGHT-EMITTING ELEMENT, AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069647-A1 Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device CRY1, CHRM1, CYP1A1 L3MBTL1 235/4885KDM4E 3714/4885ATM 2629/4885
US-20100076201-A1 Carbazole Derivative and Method for Producing the Same AADAC, CYP1A1, CYP1B1 L3MBTL1 3790/4885KDM4E 3302/4885ATM 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.