Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244589 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRELANEMAPK1L3MBTL1 | |
| SCHEMBL10458255 | 0.85 | ALDH1A1 (0.47) | POLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27793757 | 0.82 | POLB (0.43) | POLBALDH1A1GAACETPELANE | |
| SCHEMBL27793732 | 0.81 | POLB (0.43) | POLBALDH1A1GAACETPELANE | |
| SCHEMBL11067301 | 0.81 | POLB (0.48) | POLBALDH1A1GAACETPTSHR | |
| SCHEMBL10400079 | 0.81 | ELANE (0.56) | ELANELAP3 | |
| SCHEMBL8386861 | 0.80 | POLB (0.47) | POLBALDH1A1GAACETPTSHR | |
| SCHEMBL10458760 | 0.78 | GAA (0.48) | POLBALDH1A1GAACETPELANE | |
| SCHEMBL25942345 | 0.77 | ALDH1A1 (0.47) | POLBALDH1A1CETPTSHRELANE | |
| SCHEMBL3231535 | 0.76 | ALDH1A1 (0.55) | POLBALDH1A1TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969758-B2 | Antimicrobial compounds | BIOMERIEUX (FR) | 2018-05-15 | — | — | US | disclosed |
| EP-3119799-B1 | ANTIMICROBIAL COMPOUNDS | BIOMERIEUX SA (FR) | 2018-03-14 | — | — | EP | disclosed |
| US-20170158720-A1 | Antimicrobial Compounds | BIOMERIEUX (FR) | 2017-06-08 | — | — | US | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158720-A1 | Antimicrobial Compounds | NGLY1, MRPL21, VIP | POLB 1520/4885ALDH1A1 3748/4885GAA 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.