Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244589 | 0.78 | ALDH1A1 (0.50) | L3MBTL1ELANELAP3SLC1A3TDP1 | |
| SCHEMBL10458230 | 0.77 | ELANE (0.47) | ELANELAP3ANPEPTDP1KMT2A | |
| SCHEMBL11398405 | 0.75 | ATM (0.41) | ATML3MBTL1ELANESLC1A3TDP1 | |
| SCHEMBL9939655 | 0.74 | ELANE (0.53) | ATML3MBTL1ELANELAP3SLC1A3 | |
| SCHEMBL285949 | 0.74 | ELANE (0.53) | ATML3MBTL1ELANELAP3SLC1A3 | |
| SCHEMBL133568 | 0.74 | ELANE (0.53) | ATML3MBTL1ELANELAP3SLC1A3 | |
| SCHEMBL869694 | 0.74 | ATM (0.53) | ATML3MBTL1ELANESLC1A3KMT2A | |
| Ammonia Solution, Strong SCHEMBL2037585 | 0.73 | ELANE (0.51) | ATML3MBTL1ELANELAP3SLC1A3 | |
| Hydrochloric Acid SCHEMBL19834657 | 0.73 | ELANE (0.51) | ATML3MBTL1ELANELAP3SLC1A3 | |
| Ammonia Solution, Strong SCHEMBL9613925 | 0.73 | ELANE (0.51) | ATML3MBTL1ELANELAP3SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |