Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.56 |
| ▸ | GSTO1 | P78417 | 9/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796044 | 0.84 | GRM4 (0.57) | GSTO1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL30623235 | 0.84 | RORC (0.78) | RORCALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17603152 | 0.84 | RORC (0.78) | RORCALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1948433 | 0.77 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7326435 | 0.77 | RORC (0.52) | RORCMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10654061 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29678387 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30833308 | 0.76 | CYP3A4 (0.71) | GSTO1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL4003878 | 0.76 | CYP3A4 (0.71) | GSTO1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL7081917 | 0.75 | NPC1 (0.61) | GSTO1CYP3A4KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906286-A | Herbicidal 2-aryl-1,2,4-triazine-3,5(2H,4H)-diones and sulfur analogs thereof | FMC CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0185731-A4 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1988-11-02 | — | — | EP | disclosed |
| US-4766233-A | Herbicidal 2-aryl-1,2,4-triazine-3,5(2H,4H)-diones and sulfur analogs thereof | FMC CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| CN-85105721-A | Weedicide 2-aryl-1,2, and 4-triazine-3,5 (2H, 4H)-diketone and sulfur containing analogs thereof | — | 1987-09-02 | — | — | CN | disclosed |
| EP-0185731-A1 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF | FMC Corporation (US) | 1986-07-02 | — | — | EP | disclosed |
| WO-1986000072-A1 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1986-01-03 | — | — | WO | disclosed |