Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GMPS | P49915 | 2/20 | 0.55 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | RNF4 | P78317 | 1/20 | 0.51 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29678387 | 1.00 | ALDH1A1 (0.67) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL13652569 | 0.86 | MTNR1B (0.59) | ALDH1A1POLBCA2PLAUF2 | |
| SCHEMBL4544119 | 0.85 | MEN1 (0.55) | ALDH1A1CNR1CA2PLAUF2 | |
| SCHEMBL1837650 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL31390722 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL1948433 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MITFMAPK1HTTMAP2K7 | |
| SCHEMBL28633805 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL2093222 | 0.81 | CA2 (0.58) | ALDH1A1CNR1CA2PLAUF2 | |
| SCHEMBL2093226 | 0.81 | CA2 (0.58) | ALDH1A1MAPK1CNR1CA2PLAU | |
| SCHEMBL17680726 | 0.81 | CA2 (0.58) | ALDH1A1MAPK1HTTCNR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185731-A4 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0185731-A1 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF | FMC Corporation (US) | 1986-07-02 | — | — | EP | disclosed |
| WO-1986000072-A1 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1986-01-03 | — | — | WO | disclosed |