SCHEMBL10459191

SCHEMBL10459191

O=C(O)c1ccc(C=Cc2ccccc2C=Cc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.55
ALDH1A1 P00352 1/20 0.54
TSHR P16473 2/20 0.52
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
FBP1 P09467 1/20 0.52
SLC16A3 O15427 1/20 0.51
SRD5A2 P31213 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
TRPA1 O75762 1/20 0.50
SRD5A1 P18405 1/20 0.50
TP53 P04637 1/20 0.50
KMT2A Q03164 3/20 0.49
RARA P10276 1/20 0.49
RARB P10826 1/20 0.49
RARG P13631 1/20 0.49
MEN1 O00255 1/20 0.49
ATM Q13315 1/20 0.49
TTR P02766 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10459190 1.00 HDAC1 (0.55) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL11545296 0.89 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL8437189 0.89 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL1927732 0.89 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL1927729 0.89 HDAC1 (0.67) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL68551 0.89 GRIK1 (0.56) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL68552 0.89 GRIK1 (0.56) HDAC1ALDH1A1TSHRDAONAPRT
SCHEMBL5750731 0.87 CYP1A1 (0.54) HDAC1ALDH1A1FBP1SLC16A3TRPA1
SCHEMBL22553049 0.87 NFE2L2 (0.67) HDAC1ALDH1A1FBP1SLC16A3TTR
SCHEMBL22553051 0.87 NFE2L2 (0.67) HDAC1ALDH1A1FBP1SLC16A3TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0391204-A2 Process for preparing moulded articles of polymers with E-configurated stilbene moieties BAYER AG (DE) 1990-10-10 EP disclosed