Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459594 | 0.86 | DRD2 (0.36) | HTR2ADRD2DRD1ERN1HTR2C | |
| SCHEMBL10459577 | 0.84 | ERN1 (0.41) | HTR2ADRD2DRD1ERN1HTR2C | |
| SCHEMBL10459614 | 0.80 | DRD2 (0.32) | HTR2ADRD2DRD1ERN1PRKCI | |
| SCHEMBL10460363 | 0.78 | BCHE (0.33) | HTR2ADRD2DRD1ERN1 | |
| SCHEMBL10459592 | 0.77 | HTR2A (0.34) | HTR2ADRD2ERN1HTR2CHTR2B | |
| SCHEMBL10459599 | 0.76 | RAB9A (0.42) | TAS1R3TAS1R1 | |
| SCHEMBL5722666 | 0.70 | HTR2C (0.50) | HTR2AERN1HTR2CHTR2B | |
| SCHEMBL1701459 | 0.70 | AHR (0.42) | DRD2ERN1PRKCIDRD3HDAC3 | |
| SCHEMBL10459580 | 0.70 | BCHE (0.38) | HTR2ADRD2DRD1ERN1PRKCI | |
| SCHEMBL5536555 | 0.68 | ERN1 (0.41) | HTR2ADRD2DRD1ERN1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966907-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | MERCK & CO., INC. (US) | 1990-10-30 | — | — | US | disclosed |