Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112387 | 0.92 | POLB (0.54) | POLBKMT2AMEN1CYP2C9THRB | |
| SCHEMBL10909263 | 0.85 | GAA (0.52) | POLBKMT2AMEN1CYP2C9THRB | |
| SCHEMBL9818646 | 0.85 | POLB (0.46) | POLBKMT2AMEN1CYP2C9THRB | |
| SCHEMBL10566316 | 0.83 | MEN1 (0.45) | POLBKMT2AMEN1CYP2C9THRB | |
| SCHEMBL3631679 | 0.83 | ALKBH2 (0.51) | POLBKMT2AMEN1THRBCA1 | |
| SCHEMBL10454401 | 0.82 | POLB (0.43) | POLBKMT2AMEN1CYP2C9THRB | |
| SCHEMBL11063874 | 0.82 | THRB (0.46) | POLBKMT2AMEN1THRBCA1 | |
| SCHEMBL11043153 | 0.82 | MEN1 (0.53) | POLBKMT2AMEN1CYP2C9L3MBTL1 | |
| SCHEMBL10647898 | 0.81 | POLB (0.43) | POLBKMT2AMEN1CYP2C9THRB | |
| SCHEMBL10986462 | 0.81 | POLB (0.46) | POLBKMT2AMEN1CYP2C9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169719-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND CO. (US) | 1979-10-02 | — | — | US | claimed |
| US-4904778-A | Pyrimidine-2-phenylamino derivatives | CIBA-GEIGY CORP. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4802909-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| US-4169719-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND CO. (US) | 1979-10-02 | — | — | US | disclosed |