Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388720 | 0.91 | MIF (0.43) | MIFALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11805657 | 0.83 | SMN1; SMN2 (0.44) | MIFPOLBLMNANR1I2GAA | |
| SCHEMBL11802813 | 0.80 | MIF (0.46) | MIFPOLBGAAALDH1A1KDM4E | |
| SCHEMBL7282986 | 0.75 | POLB (0.49) | POLBGAAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11067301 | 0.74 | POLB (0.48) | POLBLMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL6843718 | 0.73 | POLB (0.42) | MIFPOLBLMNANR1I2ALDH1A1 | |
| SCHEMBL11115120 | 0.73 | MIF (0.54) | MIFLMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11115123 | 0.73 | MIF (0.54) | MIFLMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8386861 | 0.73 | POLB (0.47) | POLBGAAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11804685 | 0.72 | PPARG (0.43) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |