Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388720 | 0.90 | MIF (0.43) | MIFATMFABP7FABP5AURKA | |
| SCHEMBL10459830 | 0.80 | MIF (0.44) | MIFALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8228438 | 0.75 | MIF (0.52) | MIFATMAURKAGAA | |
| SCHEMBL11795802 | 0.72 | ALDH1A1 (0.50) | ATMALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL11690153 | 0.71 | LMNA (0.53) | MIFATMFABP7FABP5ALDH1A1 | |
| SCHEMBL13186028 | 0.70 | MIF (0.53) | MIFATMFABP7FABP5AURKA | |
| SCHEMBL27410647 | 0.70 | LDHA (0.55) | ATMFABP7FABP5ALDH1A1RAB9A | |
| SCHEMBL29032094 | 0.70 | MIF (0.67) | MIFALDH1A1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL7694064 | 0.69 | ALDH1A1 (0.47) | ATMFABP7FABP5ALDH1A1RAB9A | |
| SCHEMBL11802715 | 0.69 | ALDH1A1 (0.47) | MIFATMFABP7FABP5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |