SCHEMBL11067301

SCHEMBL11067301

CCOP(=O)(OCC)C(C(=O)OCc1ccccc1)P(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
CETP P11597 3/20 0.47
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
GAA P10253 1/20 0.45
HSD17B10 Q99714 1/20 0.44
ELANE P08246 1/20 0.42
FOLH1 Q04609 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KLK1 P06870 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10761143 0.85 ALDH1A1 (0.53) CETPALDH1A1TSHRMAPK1L3MBTL1
SCHEMBL7282986 0.81 POLB (0.49) POLBCETPALDH1A1TSHRGAA
SCHEMBL8386861 0.79 POLB (0.47) POLBCETPALDH1A1TSHRGAA
SCHEMBL10762480 0.77 ALDH1A1 (0.53) ALDH1A1TSHRELANEMAPK1L3MBTL1
SCHEMBL10458760 0.77 GAA (0.48) POLBCETPALDH1A1GAAHSD17B10
SCHEMBL27793757 0.76 POLB (0.43) POLBCETPALDH1A1GAAHSD17B10
SCHEMBL25942345 0.75 ALDH1A1 (0.47) POLBCETPALDH1A1TSHRHSD17B10
SCHEMBL6259612 0.75 ELANE (0.58) HSD17B10ELANEKLK1
SCHEMBL10458762 0.75 GAA (0.44) POLBCETPALDH1A1GAAHSD17B10
SCHEMBL27793732 0.75 POLB (0.43) POLBCETPALDH1A1GAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465689-A MONIC ACID ESTERS BEECHAM GROUP LIMITED (GB) 1984-08-14 US disclosed
US-4318856-A Antibacterial compounds BEECHAM GROUP LIMITED (GB) 1982-03-09 US disclosed
US-4289779-A HETEROCYCLIC ESTERS OF MONIC ACID; TREATMENT OF PENICILLIN-RESISTANT GONORRHEA BEECHAM GROUP LIMITED (GB) 1981-09-15 US disclosed
US-4283412-A MONIC ACID BEECHAM GROUP LIMITED (GB) 1981-08-11 US disclosed
US-4283411-A MONIC ACID BEECHAM GROUP LIMITED (GB) 1981-08-11 US disclosed
US-4267316-A HETEROCYCLIC ESTERS OF PSEUDOMONIC ACID; UROGENITAL DISORDERS; NEISSERIA; BRONCHIUS; VETERINARY MEDICINE BEECHAM GROUP LIMITED (GB) 1981-05-12 US disclosed
US-4256762-A ESTERS OF MONIC ACID BEECHAM GROUP LIMITED (GB) 1981-03-17 US disclosed
US-4256879-A BACTERICIDES, FURFURYLMETHYL, EPOXYPROPYL BEECHAM GROUP LIMITED (GB) 1981-03-17 US disclosed
US-4237161-A BRONCHITIS AND VENERAL DISEASE BEECHAM GROUP LIMITED (GB) 1980-12-02 US disclosed
US-4235784-A Antibacterial compounds BEECHAM GROUP LIMITED (GB) 1980-11-25 US disclosed
US-4217447-A Antibacterial compounds BEECHAM GROUP LIMITED (GB) 1980-08-12 US disclosed
US-4217448-A MONIC ACID DERIVATIVES BEECHAM GROUP LIMITED (GB) 1980-08-12 US disclosed
US-4166863-A ACTIVE AGAINST HEMOPHILUS AND NEISSERIA BEECHAM GROUP LIMITED (GB) 1979-09-04 US disclosed
US-4102901-A MONIC ACID ESTERS BEECHAM GROUP LIMITED (GB) 1978-07-25 US disclosed