Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154594 | 0.82 | ALDH1A1 (0.61) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL1638832 | 0.81 | TSHR (0.57) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL8872328 | 0.81 | TSHR (0.57) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL9735304 | 0.81 | TSHR (0.50) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL10459135 | 0.80 | TSHR (0.61) | TSHRLMNAHSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL29500171 | 0.80 | TSHR (0.65) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL27686802 | 0.80 | TSHR (0.65) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL3230316 | 0.80 | TSHR (0.65) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL396552 | 0.80 | TSHR (0.69) | TSHRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL5110148 | 0.80 | TSHR (0.56) | TSHRSCN1ASCN2ASCN3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |