Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461861 | 0.91 | KCNH2 (0.70) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10460591 | 0.90 | KCNH2 (0.58) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10461340 | 0.88 | KCNH2 (0.64) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10460724 | 0.88 | KCNH2 (0.64) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10459164 | 0.88 | KCNH2 (0.64) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10460419 | 0.88 | KCNH2 (0.64) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10461657 | 0.86 | KCNH2 (0.61) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10722742 | 0.86 | KCNH2 (0.61) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10460508 | 0.86 | KCNH2 (0.64) | KCNH2MEN1PAX8KMT2AHRH3 | |
| SCHEMBL10461280 | 0.86 | HTR1A (0.66) | KCNH2MEN1PAX8KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | claimed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |