Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352063 | 0.86 | BRD4 (0.42) | BRD4ALDH1A1ELANEMAPTSMN1; SMN2 | |
| SCHEMBL7613547 | 0.84 | ELANE (0.50) | BRD4ALDH1A1ELANEL3MBTL1CTSG | |
| SCHEMBL9762213 | 0.81 | BRD4 (0.44) | BRD4LMNAALDH1A1 | |
| SCHEMBL7613256 | 0.81 | KMT2A (0.48) | BRD4ALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL10460968 | 0.80 | BRD4 (0.54) | BRD4ALDH1A1MAP2K1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10745965 | 0.79 | BRD4 (0.36) | BRD4MAP2K1 | |
| SCHEMBL10458950 | 0.77 | BRD4 (0.42) | BRD4ALDH1A1MAP2K1 | |
| SCHEMBL9760799 | 0.75 | BRD4 (0.37) | BRD4 | |
| SCHEMBL9762493 | 0.75 | BRD4 (0.40) | BRD4ALDH1A1MAP2K1 | |
| SCHEMBL10741455 | 0.75 | BRD4 (0.44) | BRD4MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826527-A | Aminophenylmethyl isoxazolidinones as plant regulators | FMC CORPORATION (US) | 1989-05-02 | — | — | US | claimed |
| US-4892578-A | Phenylmethyl-4,4-dimethyl-3-isoxazolidinone plant regulators | FMC CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| US-4826527-A | Aminophenylmethyl isoxazolidinones as plant regulators | FMC CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4826527-A | Aminophenylmethyl isoxazolidinones as plant regulators | FMC CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| US-4692182-A | Herbicidal isoxazolidinone derivatives | FMC CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |