Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762213 | 0.81 | BRD4 (0.44) | BRD4GRM2 | |
| SCHEMBL9762493 | 0.78 | BRD4 (0.40) | BRD4 | |
| SCHEMBL7613547 | 0.78 | ELANE (0.50) | BRD4 | |
| SCHEMBL9761584 | 0.77 | BRD4 (0.36) | BRD4 | |
| SCHEMBL2352063 | 0.76 | BRD4 (0.42) | BRD4GRM2 | |
| SCHEMBL9762586 | 0.76 | PARG (0.37) | BRD4 | |
| SCHEMBL10460973 | 0.75 | BRD4 (0.39) | BRD4 | |
| SCHEMBL9761609 | 0.75 | CHRM5 (0.41) | BRD4 | |
| SCHEMBL7613256 | 0.72 | KMT2A (0.48) | BRD4KAT2B | |
| Hydrochloric Acid SCHEMBL10745965 | 0.70 | BRD4 (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |