Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613547 | 0.84 | ELANE (0.50) | BRD4ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9762493 | 0.84 | BRD4 (0.40) | BRD4ALDH1A1KDM4E | |
| SCHEMBL2352063 | 0.83 | BRD4 (0.42) | BRD4ALDH1A1KDM4EGRM2CA9 | |
| SCHEMBL9760799 | 0.81 | BRD4 (0.37) | BRD4GRM2 | |
| SCHEMBL10460973 | 0.81 | BRD4 (0.39) | BRD4ALDH1A1LMNA | |
| SCHEMBL7613256 | 0.78 | KMT2A (0.48) | BRD4ALDH1A1CYP2D6CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL10745965 | 0.76 | BRD4 (0.36) | BRD4 | |
| SCHEMBL9761664 | 0.75 | BRD4 (0.47) | BRD4ALDH1A1KDM4ECYP2C19LMNA | |
| SCHEMBL9761584 | 0.74 | BRD4 (0.36) | BRD4CYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9762147 | 0.74 | BRD4 (0.43) | BRD4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066665-A | Cognition activators; alzheimer*s disease | WARNER-LAMBERT CO. (US) | 1991-11-19 | — | — | US | disclosed |