Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462371 | 0.93 | TBXA2R (0.59) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10463686 | 0.90 | TBXA2R (0.69) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10461761 | 0.90 | TBXA2R (0.56) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10461966 | 0.88 | TBXA2R (0.54) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10460671 | 0.88 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL11106768 | 0.88 | ALDH1A1 (0.64) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10464058 | 0.87 | TBXA2R (0.53) | TBXA2RMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8593388 | 0.87 | TBXAS1 (0.58) | TBXA2RALDH1A1LMNATBXAS1MAPT | |
| SCHEMBL9129860 | 0.86 | TSHR (0.65) | TBXA2RMEN1KMT2AALDH1A1TBXAS1 | |
| SCHEMBL10463281 | 0.86 | AKR1C3 (0.56) | TBXA2RMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |
| US-4443477-A | ANTICOAGULANTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-17 | — | — | US | disclosed |
| EP-0031954-B1 | SULPHONAMIDES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1984-03-14 | — | — | EP | disclosed |