Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463119 | 0.94 | AKR1C3 (0.54) | AKR1C3ALDH1A1LMNATBXA2RMAPT | |
| SCHEMBL10463635 | 0.91 | AKR1C3 (0.53) | AKR1C3ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL10463521 | 0.88 | AKR1C3 (0.48) | AKR1C3ALDH1A1LMNATBXA2RMAPT | |
| SCHEMBL10461981 | 0.86 | TBXA2R (0.62) | AKR1C3ALDH1A1LMNATBXA2RMAPT | |
| SCHEMBL11106768 | 0.86 | ALDH1A1 (0.64) | AKR1C3ALDH1A1LMNATBXA2RMAPT | |
| SCHEMBL11107020 | 0.86 | AKR1C3 (0.60) | AKR1C3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11108646 | 0.84 | AKR1C3 (0.50) | AKR1C3ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL10461985 | 0.80 | AKR1C3 (0.58) | AKR1C3ALDH1A1MAPTSMN1; SMN2RECQL | |
| SCHEMBL10462371 | 0.80 | TBXA2R (0.59) | AKR1C3ALDH1A1LMNATBXA2RKMT2A | |
| SCHEMBL11107840 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |