Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SLC5A1 | P13866 | 6/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463769 | 0.88 | ALDH1A1 (0.54) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL10463764 | 0.84 | TP53 (0.40) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL17321554 | 0.72 | MAPK1 (0.49) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL17321555 | 0.72 | TP53 (0.71) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL25767433 | 0.70 | TP53 (0.67) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL14511339 | 0.70 | TSHR (0.49) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL10464748 | 0.69 | PDE4B (0.39) | TP53ALOX12KMT2AALDH1A1HSD17B10 | |
| SCHEMBL15881976 | 0.69 | ALDH1A1 (0.46) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL15897945 | 0.69 | TP53 (0.66) | TP53ALOX12SLC5A1SLC5A2KMT2A | |
| SCHEMBL14692205 | 0.69 | TP53 (0.49) | TP53ALOX12SLC5A1SLC5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959479-A | PESTICIDES, DRUGS | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1990-09-25 | — | — | US | disclosed |
| US-4889937-A | MEDICINES, PESTICIDES AND INDUSTRIAL CHEMICALS | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1989-12-26 | — | — | US | disclosed |