Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.52 |
| ▸ | SPR | P35270 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457023 | 0.88 | SLC5A1 (0.59) | TP53ALOX12NPSR1ALDH1A1MAPT | |
| SCHEMBL20162908 | 0.86 | GAA (0.51) | TP53ALOX12NPSR1ALDH1A1KMT2A | |
| SCHEMBL30036841 | 0.86 | GAA (0.51) | TP53ALOX12NPSR1ALDH1A1KMT2A | |
| SCHEMBL17321555 | 0.86 | TP53 (0.71) | TP53ALOX12NPSR1ALDH1A1MITF | |
| SCHEMBL3455812 | 0.86 | NPSR1 (0.55) | TP53ALOX12NPSR1ALDH1A1MITF | |
| SCHEMBL23771920 | 0.85 | NPSR1 (0.57) | TP53ALOX12NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19997265 | 0.84 | PTGS2 (0.51) | TP53ALOX12NPSR1ALDH1A1MAPT | |
| SCHEMBL3455998 | 0.84 | NPSR1 (0.53) | TP53ALOX12NPSR1ALDH1A1KMT2A | |
| SCHEMBL15897945 | 0.83 | TP53 (0.66) | TP53ALOX12ALDH1A1MITFSMN1; SMN2 | |
| SCHEMBL3455838 | 0.82 | ALDH1A1 (0.57) | TP53ALOX12NPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691992-B2 | Oxaborole analogs and uses thereof | ANACOR PHARMACEUTICALS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691992-B2 | Oxaborole analogs and uses thereof | OXA1L, EPX, OAT | TP53 4500/4885ALOX12 275/4885NPSR1 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.