Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464748 | 0.89 | PDE4B (0.39) | TP53ALOX12ALDH1A1HSD17B10TSHR | |
| SCHEMBL10463199 | 0.84 | TP53 (0.52) | TP53ALOX12ALDH1A1HSD17B10SLC5A1 | |
| SCHEMBL10463775 | 0.81 | TUBB4A (0.34) | TP53ALDH1A1HSD17B10SLC5A1SLC5A2 | |
| SCHEMBL10463922 | 0.80 | CYP1A2 (0.36) | ALDH1A1HSD17B10TSHRKMT2AADORA3 | |
| SCHEMBL10464236 | 0.78 | ALOX15 (0.47) | ALDH1A1KMT2AGAAHPGDMEN1 | |
| SCHEMBL10463769 | 0.77 | ALDH1A1 (0.54) | TP53ALOX12ALDH1A1HSD17B10SLC5A1 | |
| SCHEMBL10461607 | 0.72 | KMT2A (0.51) | ALOX12ALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL10463778 | 0.71 | ALOX15 (0.41) | ALDH1A1KMT2AGAAKDM4EHPGD | |
| SCHEMBL8795115 | 0.66 | RXFP1 (0.62) | ALDH1A1KMT2AGAALMNAHPGD | |
| SCHEMBL8794998 | 0.66 | GAA (0.58) | TP53ALDH1A1TSHRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959479-A | PESTICIDES, DRUGS | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1990-09-25 | — | — | US | claimed |
| US-4959479-A | PESTICIDES, DRUGS | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1990-09-25 | — | — | US | disclosed |
| US-4889937-A | MEDICINES, PESTICIDES AND INDUSTRIAL CHEMICALS | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1989-12-26 | — | — | US | disclosed |